A Family with Thromboembolic Disease Associated with Deficient Fibrinolytic Activity in Vessel Wall
- 12 January 1978
- journal article
- research article
- Published by Wiley in Acta Medica Scandinavica
- Vol. 203 (1-6) , 477-480
- https://doi.org/10.1111/j.0954-6820.1978.tb14911.x
Abstract
Defective fibrinolytic activity is often a contributory factor in deep venous thrombosis. A family with a high incidence of venous thrombosis in association with such a defect is presented. Of 13 family members who had had thrombosis, 12 showed a defective capacity to release fibrinolytic activity from vessel wall after venous occlusion and/or infusion of DDAVP, a vasopressin derivate. The fibrinolytic activator activity of the vessel wall was normal in all cases. This seems to be the first family in which there is evidence of an inherited abnormal fibrinolytic activity.This publication has 17 references indexed in Scilit:
- Phenformin and Ethyloestrenol in Recurrent Venous ThrombosisActa Medica Scandinavica, 1975
- Antithrombin-III deficiency in a Dutch familyJournal of Clinical Pathology, 1973
- Immunologic Studies in Haemophilia AScandinavian Journal of Haematology, 1973
- Demonstration of Low Content of Fibrinolytic Inhibitors in Individuals with High Fibrinolytic CapacityScandinavian Journal of Clinical and Laboratory Investigation, 1970
- LOW FIBRINOLYTIC ACTIVITY IN THE WALLS OF VEINS IN PATIENTS WITH THROMBOSISActa Medica Scandinavica, 1969
- A Group of Patients with Impaired Plasma Fibrinolytic System and Selective Inhibition of Tissue Activator‐Induced FibrinolysisScandinavian Journal of Haematology, 1966
- Studies on a family with an elevated plasmalevel of factor V (proaccelerin) and a tendency to thrombosisThe Journal of Pediatrics, 1966
- Severe Thrombotic Disease in a Young Man with Bone Marrow and Skeletal Changes and with a High Content of an Inhibitor in the Fibrinolytic SystemActa Medica Scandinavica, 1961
- A Modification for Routine Laboratory Use of Stefanini's Method of Estimating Factor V Activity in Human Oxalated PlasmaJournal of Clinical Pathology, 1953
- The Control of Dicumarol Therapy and the Quantitative Determination of Prothrombin and ProconvertinScandinavian Journal of Clinical and Laboratory Investigation, 1951