PAR4, but Not PAR1, Signals Human Platelet Aggregation via Ca2+ Mobilization and Synergistic P2Y12 Receptor Activation
Open Access
- 1 September 2006
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 281 (36) , 26665-26674
- https://doi.org/10.1074/jbc.m602174200
Abstract
No abstract availableKeywords
This publication has 56 references indexed in Scilit:
- The small GTPase Rap1b regulates the cross talk between platelet integrin α2β1 and integrin αIIbβ3Blood, 2006
- Molecular mechanism and functional implications of thrombin-mediated tyrosine phosphorylation of PKCδ in plateletsBlood, 2005
- Interaction between a genetic variant of the platelet fibrinogen receptor and fibrinogen levels in determining the risk of cardiovascular eventsAmerican Heart Journal, 2004
- Identification of P2Y12-dependent and -independent mechanisms of glycoprotein VI–mediated Rap1 activation in plateletsBlood, 2003
- Relationships between Rap1b, Affinity Modulation of Integrin αIIbβ3, and the Actin CytoskeletonJournal of Biological Chemistry, 2002
- Activation of Rap1B by Gi Family Members in PlateletsPublished by Elsevier ,2002
- Vascular-Bed–Specific Hemostasis and Hypercoagulable StatesNew England Journal of Medicine, 1999
- A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE)The Lancet, 1996
- The Pathogenesis of Coronary Artery Disease and the Acute Coronary SyndromesNew England Journal of Medicine, 1992
- Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activationCell, 1991