Cardiomyocytes differentiated in vitro from embryonic stem cells developmentally express cardiac-specific genes and ionic currents.
- 1 August 1994
- journal article
- abstracts
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 75 (2) , 233-244
- https://doi.org/10.1161/01.res.75.2.233
Abstract
Cardiomyocytes differentiated in vitro from pluripotent embryonic stem (ES) cells of line D3 via embryo-like aggregates (embryoid bodies) were characterized by the whole-cell patch-clamp technique ...Keywords
This publication has 31 references indexed in Scilit:
- Tetrodotoxin-sensitive Sodium Current in Rat Fetal Ventricular Myocytes - Contribution to the plateau phase of action potentialJournal of Molecular and Cellular Cardiology, 1993
- Expression of thelacZ gene targeted to the HPRT locus in embryonic stem cells and their derivativesTransgenic Research, 1993
- Single-channel recording of inwardly rectifying potassium currents in developing myocardiumJournal of Molecular and Cellular Cardiology, 1991
- Developmental changes in the calcium currents in embryonic chick ventricular myocytesThe Journal of Membrane Biology, 1991
- Regulation of Cardiac L-Type Calcium Current by Phosphorylation and G ProteinsAnnual Review of Physiology, 1990
- Chloride current in mammalian cardiac myocytes. Novel mechanism for autonomic regulation of action potential duration and resting membrane potential.The Journal of general physiology, 1990
- Developmental increases in the inwardly-rectifying K+ current of embryonic chick ventricular myocytesBiochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1990
- Development of the fast sodium current in early embryonic chick heart cellsThe Journal of Membrane Biology, 1988
- Cadmium-induced blockade of the cardiac fast Na channels in calf Purkinje fibresProceedings of the Royal Society of London. B. Biological Sciences, 1985
- DNA transformation of a pluripotent mouse embryonal stem cell line with a dominant selective markerCell Differentiation, 1984