The Synthesis of Novel HIV-Protease Inhibitors via Silica Gel Assisted Addition of Amines to Epoxides
- 1 January 1993
- journal article
- letter
- Published by Georg Thieme Verlag KG in Synlett
- Vol. 1993 (09) , 703-704
- https://doi.org/10.1055/s-1993-22579
Abstract
HIV-protease inhibitors, containing novel ß-hydroxy secondary amine transition state isosteres, are constructed using a silica gel mediated addition of unreactive amines to epoxides as the key step.Keywords
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