EXPERIMENTAL PYELONEPHRITIS .5. FUNCTIONAL CHARACTERISTICS OF PYELONEPHRITIS

  • 1 January 1978
    • journal article
    • research article
    • Vol. 15  (5) , 397-400
Abstract
Changes in renal and ureteral function were studied in monkeys [Macaca arctoides] with experimental pyelonephritis and correlated with the findings of 131I-hippuran scintiphotos. During the acute phase, delayed excretion of radionuclide was a combined result of prolonged intrarenal and ureteral transit times. During the chronic phase, scintiphoto studies revealed decreased renal uptake of radionuclide suggesting decreased renal blood flow. Subsequent individual renal function studies confirmed the decrease in renal function and provided data that strongly support the intact nephron hypothesis in chronic pyelonephritis.

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