Lanthanide Trifluoromethanesulfonates as Stable Lewis Acids in Aqueous Media. Yb(OTf)3 Catalyzed Hydroxymethylation Reaction of Silyl Enol Ethers with Commercial Formaldehyde Solution
- 1 December 1991
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 20 (12) , 2187-2190
- https://doi.org/10.1246/cl.1991.2187
Abstract
Silyl enol ethers smoothly react with commercial formaldehyde solution to give the corresponding hydroxymethylated adducts in high yields by the promotion of a catalytic amount of ytterbium(III) triflate (Yb(OTf)3), which is a stable Lewis acid in aqueous media. Other lanthanide triflates are also found to be effective.This publication has 25 references indexed in Scilit:
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