Antibiotics from gliding bacteria. No.62. Disorazol A, an Efflcient Inhibitor of Eukaryotic Organisms Isolated from Myxobacteria.

Publisher Website
Google Scholar
Abstract
A new antibiotic, disorazol, was isolated from the culture broth of the myxobacterium, Sorangium cellulosum strain So ce 12. It is a macrocyclic compound containing two oxazole rings. The antibiotic acted against many fungi and mammalian cell cultures. The latter responded to extremely low doses (MIC 3-30 pg/ml). None of the tested bacteria and yeasts were inhibited.