The epidemiology of malignant neoplasia of the larynx in Canada: 1931-1984
- 1 August 1989
- journal article
- research article
- Published by Wiley in Clinical Otolaryngology
- Vol. 14 (4) , 349-355
- https://doi.org/10.1111/j.1365-2273.1989.tb00383.x
Abstract
Canadian patterns of morbidity and mortality from laryngeal carcinoma were examined for the periods 1970-1980 and 1931-1984, respectively. Age-standardized morbidity rates had risen significantly in both males and females (P=0.0001 and 0.0116) during 1970-1980 with rates for males increasing by more than 0.28 additional case per 100,000 population per year since 1970. Analysis of age-specific rates over time indicates that the rise in standardized rates is attributable to significant increases in rates for males aged 45-54, 55-64 and 65-74 (P<0.006) and females aged 45-54, 55-64, and 75-84 (P<0.045). Rates for males aged 55-64 demonstrated the most dramatic rate of change of any age group at over 1.8 additional new cases per 100,000 population per year since 1970. Analysis of age-standardized mortality rates reveals that rates for males have risen significantly during the period 1931-1984 whereas rates for females have declined significantly (P=0.0001 and 0.005, respectively). The rise in age-standardized mortality rates for males is associated with corresponding significant rates of increase in age-specific rates for males aged 45-54, 55-64, 65-74, 75-84 and 85+ (P <0.02) whereas the decline in rates for females is associated with significant declines in rates for women aged 35-44, 45-54, and 75-84 (P<0.05). Males aged 75-84 had the greatest rate of change at 0.20 additional new deaths per 100,000 population per year since 1931.Keywords
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