Synthesis of myo-inositol 1,4-bisphosphate-5-phosphorothioate
- 1 January 1989
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 5,p. 269-271
- https://doi.org/10.1039/c39890000269
Abstract
Synthesis of myo-insoitol 1,4,5-triphosphate and myo-inositol 1,4,-bisphosphate-5-phosphorothioate, a phosphatase-resistant analogue of a biological second messenger, have been accomplished using a novel combination of PIII and PV chemistry and a new deprotection method for the 2,2,2-trichloroethyl group.Keywords
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