Absorbable gelatin sponge B.P. (sterispon) and poststapedectomy sensorineural hearing loss: A phase contrast microscopic report on the human temporal bone

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Abstract
This inquiry into the oto-toxic property of absorbable gelatin sponge (Sterispon) was stimulated by a single case of poststapedectomy Sterispon granuloma associated with sensorineural hearing loss. The clinical features and phase contrast microscopic picture of the temporal bones, of a patient who died about 1 yr after a stapedectomy are presented. The right temporal bone showed complete loss of outer hair cells in the 1st 11 mm of the basal coil of the cochlea compared with the contralateral side in which the outer hair cells were absent for up to 5mm of the basal coil only. At least some of the damage to the outer hair cells in the basal coil of the right human cochlea may be due to small quantities of formaldehyde.

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