Endothelium and inelastic arteries: an early marker of vascular dysfunction in non-insulin dependent diabetes
- 23 March 1996
- Vol. 312 (7033) , 744-745
- https://doi.org/10.1136/bmj.312.7033.744
Abstract
We studied 12 symptom free, non-smoking, healthy patients (six men) with well controlled non-insulin dependent diabetes diabnosed 1-7 (mean 3.8) years previously (mean age 50 (SD 9) years, body mass index 26.9 (4.8) kg/m2, serum cholesterol concentration 5.8 (0.5) mmol/l). Patients with known causes of endothelial dysfunction were excluded. All patients had insulin resistance with basal hyperinsulinaemia,2 no biochemical evidence of renal impairment, and no microalbuminuria. A group of 12 normal non-smoking subjects was matched for sex, age, body mass index, blood pressure, and serum cholesterol concentration and served as a control group.Keywords
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