Cycloheximide: Its Effects on Activity Are Dissociable from Its Effects on Memory
- 2 April 1971
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 172 (3978) , 82-84
- https://doi.org/10.1126/science.172.3978.82
Abstract
Cycloheximide, when injected subcutaneously or intracerebrally, produces changes in the activity level of mice. Isocycloheximide, injected intracerebrally, produces identical effects on activity, but it does not produce inhibition of cerebral protein synthesis or amnesia. Amphetamine, in doses that can antagonize the amnesic action of cycloheximide, does not antagonize the effect of cycloheximide on activity. Effects of cycloheximide on activity do not appear to be responsible for its amnesic action.Keywords
This publication has 4 references indexed in Scilit:
- Cerebral Protein Synthesis Inhibitors Block Long-Term MemoryPublished by Elsevier ,1970
- Puromycin Effect on Memory May Be Due to Occult SeizuresScience, 1967
- Puromycin and Cycloheximide: Different Effects on Hippocampal Electrical ActivityScience, 1966
- Puromycin Effect on Successive Phases of Memory StorageScience, 1966