Synthesis of compounds related to antihemorrhagic vitamin K. III: 1,4‐naphthoquinone as a starting material for the preparation of 2‐methyl‐1,4‐naphtho‐hydroquinone and derivatives
- 1 January 1940
- journal article
- research article
- Published by Wiley in Recueil des Travaux Chimiques des Pays-Bas
- Vol. 59 (11) , 1029-1035
- https://doi.org/10.1002/recl.19400591102
Abstract
A general method for the synthesis of 2‐alkyl‐1,4‐naphthoquinones and hydroquinones from 1,4‐naphthoquinone as the starting material is described in this paper, with special references to 2‐methyl‐1,4‐naphthoquinone, 2‐methyl‐1,4‐naphtho‐hydroquinone, the dimethyl ether, the diacetate, the dipropionate, and the dibenzoate of the synthetic 2‐methyl‐1,4‐naphtho‐hydroquinone, which have recently been shown to possess strong anti‐hemorrhagic vitamin K activity.Keywords
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