The Reaction of Singlet Oxygen with 1,3‐Dimethylindole in the Presence of Aldehydes. Formation of 1,2,4‐Trioxanes

Abstract
The dye‐sensitized photo‐oxygenation of 1,3‐dimethylindole in the presence of aldehydes initially generates a zwitterionic peroxide which condenses with the carbonyl function to give the corresponding cis‐fused 1,2,4‐trioxanes. Acetaldehyde gives a pair of diastereomers, one of whose structures was determined by X‐ray analysis (cis,cisisomer), whereas pivaladehyde gives only the cis,cis diastereomer.

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