Degradation of DNA in High-Intensity Focused Ultrasonic Fields at 1 MHz
- 1 December 1971
- journal article
- research article
- Published by Acoustical Society of America (ASA) in The Journal of the Acoustical Society of America
- Vol. 50 (6B) , 1539-1545
- https://doi.org/10.1121/1.1912808
Abstract
Gassy and degassed aqueous solutions of DNA were treated ultrasonically while monitoring the field for discrete cavitation events. At irradiation intensities greater than about 500 W/cm2, transient cavitation is shown to be responsible for the observed reduction in molecular weight. At intensities of 200 to 288 W/cm2, degradation of DNA was observed which did not depend upon transient cavitation.Keywords
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