Smaller Auditory P300 Amplitude in Schizophrenics in Remission
- 1 January 1995
- journal article
- pharmacoelectroencephalography
- Published by S. Karger AG in Neuropsychobiology
- Vol. 32 (3) , 171-174
- https://doi.org/10.1159/000119231
Abstract
The P300 event-related potential (ERP) was recorded using the auditory oddball paradigm in 12 (6 male) schizophrenic (DSM-IIIR) patients in rigorously defined clinical remission. The ERP was also recorded in 10 (5 male) age-, sex-and education-matched control subjects. ERP latencies and amplitude were measured at Cz and Pz recording sites. Mean latencies of the P300 in schizophrenic patients in remission at Cz [343.6 ±31 (SD) ms] and Pz (346.15 ± 30 ms) did not differ from those of normals (Cz: 332.8 ± 23 ms, Pz: 323 ± 38 ms). The P300 ERP amplitude was significantly (pKeywords
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