High frequency of SEN virus infection in thalassemic patients and healthy blood donors in Iran
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Open Access
- 2 January 2010
- journal article
- research article
- Published by Springer Nature in Virology Journal
- Vol. 7 (1) , 1
- https://doi.org/10.1186/1743-422x-7-1
Abstract
SEN virus is a blood-borne, circular ssDNA virus and possessing nine genotypes (A to I). Among nine genotypes, SENV-D and SENV-H genotypes have the strong link with patients with unknown (none-A to E) hepatitis infections. Infection with blood-borne viruses is the second important cause of death in thalassemic patients. The aim of this study was to determine the frequency of SENV-D and SENV-H genotypes viremia by performing nested-PCR in 120 and 100 sera from healthy blood donors and thalassemic patients in Guilan Province, North of Iran respectively. Also, to explicate a possible role of SEN virus in liver disease and established changes in blood factors, the serum aminotransferases (ALT and AST) and some of the blood factors were measured.This publication has 25 references indexed in Scilit:
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