Hormonal Therapy for Prostate Cancer

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Abstract
Most patients with a diagnosis of prostate cancer already have metastases or will have them despite treatment aimed at the primary tumor in the prostate gland. The axial skeleton is the predominant site of dissemination; bone pain is the usual source of the patient's discomfort and debility. Although symptomatic relief is always temporary and sometimes incomplete, hormonal treatments can palliate the symptoms in the majority of patients, making prostatic cancer the tumor most responsive to hormonal therapy.Reduction of serum testosterone levels is a common feature of effective hormonal therapy in this disease. It can be achieved with orchiectomy, with . . .