Evidence for the Neutral Hypothesis of Protein Polymorphism
- 6 October 1972
- journal article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 178 (4056) , 56-58
- https://doi.org/10.1126/science.178.4056.56
Abstract
Data for some 400 polymorphic proteins were examined with special reference to molecular evolution, by using a statistic that depends on neither mutation rate, population structure, nor other ecological factors. The result indicates that most of these polymorphisms are maintained in a population by mutation and random genetic drift.Keywords
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