Intravenous Phenytoin

Publisher Website
Google Scholar
Abstract
To the Editor: The appropriate mode of administering intravenous phenytoin is of considerable clinical importance. Sellers and Kalant1 suggested that the desired dose be added to a large volume of 5 per cent dextrose in water and then infused intravenously over one to four hours. We have made a similar recommendation.2 Correspondents in the Journal, however, hastened to point out that these recommendations constituted a "gross error" because "a precipitate is readily apparent" when phenytoin is added to 5 per cent dextrose in water or physiologic saline.3 To assess the rate and extent of phenytoin precipitation upon mixture . . .

This publication has 3 references indexed in Scilit: