Mdr1 Transfection Causes Enhanced Apoptosis by Paclitaxel: An Effect Independent of Drug Efflux Function of P-Glycoprotein
- 1 January 2001
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 18 (7) , 907-913
- https://doi.org/10.1023/a:1010919823936
Abstract
Purpose. We previously reported that in patient tumors the expression of the mdr1 p-glycoprotein (Pgp) resulted in a lower paclitaxel-induced inhibition of DNA precursor incorporation, but a higher...Keywords
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