Role of Heparin in in vitro Production of Alpha1 Lipoproteins in Human Plasma

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Abstract
An absolute increase in high-density alpha1 lipoproteins, and a concomitant decrease in certain low density lipoproteins, was demonstrated by ultracentrifugal and chemical means. These changes occurred in vitro in plasma obtained after heparin injns. and suggest, on the basis of earlier studies on the nature of the lipemia-clearing reaction, an enzymatic conversion of 1 lipoprotein class to another.

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