The genodermatopathology of adnexal tumors

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Abstract
Several adnexal tumors (e.g., triehoepitheliomas, trichilemmomas. steatocystomas. sebaceous adenomas, and cylindromas) tend to occur as multiple lesions showing autosomal dominant inheritance, sometimes in association with other cutaneous or internal findings. Solitary tumors with the same clinical and histopathologic features are usually trivial non‐hereditary lesions. Multiple trichilemmomas are part of Cowden's syndrome, which includes a high incidence of breast cancer in women; multiple sebaceous adenomas and other sebaceous tumors associated with carcinomas of the gastrointestinal tract arc part of a syndrome that was first delineated by Bakker and Tjon A Joe.

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