COMPARISON OF MEPTAZINOL AND PETHIDINE GIVEN I.V. ON DEMAND IN THE MANAGEMENT OF POSTOPERATIVE PAIN
Open Access
- 1 September 1981
- journal article
- research article
- Published by Elsevier in British Journal of Anaesthesia
- Vol. 53 (9) , 927-931
- https://doi.org/10.1093/bja/53.9.927
Abstract
Meptazinol and pethidine were compared under double-blind conditions in 20 patients, using an on-demand analgesic system to provide pain relief after upper abdominal surgery. The degree of analgesia, subjectively assessed, was good with both meptazinol and pethidine; although meptazinol produced significantly more nausea than did pethidine (P<0.01), there was no statistically significant difference in the frequency of other side-effects. Over 24h average consumption of meptazinol was 2.4 times that of pethidine, suggesting that, when given by i.v. injection, meptazinol is less potent than pethidine.Keywords
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