A DAST-free route to aryl(difluoromethyl)phosphonic esters

Abstract
The cerium(III)-mediated addition of diethyl (lithiodifluoromethyl)phosphonate to a benzoquinone monoketal allows the synthesis of phenol bearing the (diethoxyphosphonyl)difluoromethyl group via short, scaleable reaction sequences which avoid the use of the DAST reagent.

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