Effect of Small Doses of Estrogen on Serum Lipids in Female Patients with Myocardial Infarction

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Abstract
IN 1949 Eilert1 made the original observation that estrogen administration raised the serum phospholipid and lowered the serum cholesterol and cholesterol-phospholipid ratio in female patients. Since these observations and the classic studies in laboratory animals recently summarized by Stamler, Pick and Katz,2 much interest has been directed toward assessing the clinical value of estrogen in atherosclerosis and particularly in myocardial infarction. Although no conclusion is yet possible in that respect, the estrogen lipid observations of Eilert have been confirmed and extended to male subjects by Russ, Eder and Barr,3 Steiner, Payson and Kendall,4 Oliver and Boyd5 and Robinson et al. . . .