γ-secretases: from cell biology to therapeutic strategies

This publication has 160 references indexed in Scilit:

• Effect of Tarenflurbil on Cognitive Decline and Activities of Daily Living in Patients With Mild Alzheimer DiseaseA Randomized Controlled Trial
  JAMA, 2009
• Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
  Nature Genetics, 2009
• Presenilins are essential for regulating neurotransmitter release
  Nature, 2009
• NOTCH inhibition and glucocorticoid therapy in T-cell acute lymphoblastic leukemia
  Leukemia, 2009
• γ-secretase inhibitors reverse glucocorticoid resistance in T cell acute lymphoblastic leukemia
  Nature Medicine, 2008
• Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
  Published by Elsevier ,2008
• Phase 2 Safety Trial Targeting Amyloid β Production With a γ-Secretase Inhibitor in Alzheimer Disease
  Archives of Neurology, 2008
• Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating
  Published by Elsevier ,2008
• Substrate-targeting γ-secretase modulators
  Nature, 2008
• Presenilins Form ER Ca2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations
  Cell, 2006