EFFECT OF LONG-WAVE ULTRAVIOLET-LIGHT ON LENS .1. MODEL SYSTEMS FOR DETECTING AND MEASURING EFFECT ON LENS INVITRO

  • 1 January 1976
    • journal article
    • research article
    • Vol. 15  (5) , 405-407
Abstract
Rat, mouse and chick lenses incubated with 3-aminotriazole under long-wave UV light showed reduced accumulation and incorporation of leucine and a loss of glutathione. The effect on leucine incorporation was strikingly enhanced when capsule-epithelium pools were incubated. The procedure may identify photosensitizers or metabolic inhibitors which are cataractogenic when acting in conjunction with UV.

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