GeMInA, Genomic Metadata for Infectious Agents, a geospatial surveillance pathogen database
Open Access
- 22 October 2009
- journal article
- research article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 38 (Database) , D754-D764
- https://doi.org/10.1093/nar/gkp832
Abstract
The Gemina system (http://gemina.igs.umaryland.edu) identifies, standardizes and integrates the outbreak metadata for the breadth of NIAID category A–C viral and bacterial pathogens, thereby providing an investigative and surveillance tool describing the Who [Host], What [Disease, Symptom], When [Date], Where [Location] and How [Pathogen, Environmental Source, Reservoir, Transmission Method] for each pathogen. The Gemina database will provide a greater understanding of the interactions of viral and bacterial pathogens with their hosts and infectious diseases through in-depth literature text-mining, integrated outbreak metadata, outbreak surveillance tools, extensive ontology development, metadata curation and representative genomic sequence identification and standards development. The Gemina web interface provides metadata selection and retrieval of a pathogen's; Infection Systems (Pathogen, Host, Disease, Transmission Method and Anatomy) and Incidents (Location and Date) along with a hosts Age and Gender. The Gemina system provides an integrated investigative and geospatial surveillance system connecting pathogens, pathogen products and disease anchored on the taxonomic ID of the pathogen and host to identify the breadth of hosts and diseases known for these pathogens, to identify the extent of outbreak locations, and to identify unique genomic regions with the DNA Signature Insignia Detection Tool.Keywords
This publication has 9 references indexed in Scilit:
- BioCaster: detecting public health rumors with a Web-based text mining systemBioinformatics, 2008
- The Microbial Rosetta Stone: a database system for tracking infectious microorganismsInternational journal of legal medicine, 2008
- HealthMap: Global Infectious Disease Monitoring through Automated Classification and Visualization of Internet Media ReportsJournal of the American Medical Informatics Association, 2008
- The value of ProMED-mail for the Early Warning Committee in the Netherlands: more specific approach recommended.2008
- The OBO Foundry: coordinated evolution of ontologies to support biomedical data integrationNature Biotechnology, 2007
- A Chado case study: an ontology-based modular schema for representing genome-associated biological informationBioinformatics, 2007
- Relations in biomedical ontologiesGenome Biology, 2005
- The Microbial Rosetta Stone Database: A compilation of global and emerging infectious microorganisms and bioterrorist threat agentsBMC Microbiology, 2005
- Doxycycline-regulated gene expression in the opportunistic fungal pathogen Aspergillus fumigatusBMC Microbiology, 2005