Predicting drug efficacy: knockouts model pipeline drugs of the pharmaceutical industry

• 1 October 2003
• journal article
• review article
• Published by Elsevier in Current Opinion in Pharmacology
• Vol. 3  (5) , 563-570
• https://doi.org/10.1016/j.coph.2003.04.002

Abstract

Keywords

• ACAT
• ACYL-COA CHOLESTEROL ACYLTRANSFERASE
• COPD
• CHRONIC OBSTRUCTIVE PULMONARY DISEASE
• CTLA4
• CYTOTOXIC T LYMPHOCYTE ANTIGEN 4
• EDG
• ENDOTHELIAL DIFFERENTIATION GENE
• EGF
• EPIDERMAL GROWTH FACTOR
• GLP-1
• GLUCAGON-LIKE PEPTIDE-1
• IMMUNOGLOBULIN
• KNOCKOUT
• NEUROKININ
• PKC
• PROTEIN KINASE C
• TACE
• TNF-Α-CONVERTING ENZYME
• TNF-Α