Quantitative Over-Pressure Layer Chromatography of Quinine, Quinidine, and Hydroquinidinein Biomedical Analysis
- 1 June 1990
- journal article
- research article
- Published by Taylor & Francis in Journal of Liquid Chromatography
- Vol. 13 (10) , 1991-1999
- https://doi.org/10.1080/01483919008049007
Abstract
An over-pressure layer chromatography (OPLC) method for the separation and quantification of quinine, quinidine and hydroquinidine is discussed in this paper. After the development with the mobile phase méthanol-acétonitrile-ammonia 0,2M (130: 68 : 2, v/v), a densitometric detection was performed by the fluorescence emission (excitation wavelength = 348 nm; emission wavelengh = 420 nm). This technique is simple, fast and adapted to small series of determination for the quality control and therapeutic drug monitoring.This publication has 10 references indexed in Scilit:
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