The Effect of Epistasis in the Standard Two-Locus Model
- 1 January 1973
- journal article
- research article
- Published by CSIRO Publishing in Australian Journal of Biological Sciences
- Vol. 26 (1) , 181-188
- https://doi.org/10.1071/bi9730181
Abstract
Moran (1964) proved three negative results for the standard two-locus model of population genetics: (1) that mean fitness was not a function of the allelic frequencies alone; (2) that stationary states of the population do not, in general, correspond to stationary values of the mean fitness; (3) the mean fitness of a population may decrease from one generation to the next.Keywords
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