Photocatalysed addition of pyrrolidines to butenolides: a concise synthesis of the pyrrolizidine alkaloid ring system

Abstract
The regiospecific and stereoselective photocatalysed addition of N-substituted pyrrolidines to 5(S)-substituted furan-2-(5H)-ones (butenolides), and subsequent conversion of the adduct from N-(trimethylsilyl)pyrrolidine into the 1-azabicyclo[3.3.0]octane ring system of the pyrrolizidine alkaloids are described.

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