Genomic Priorities in Aging
- 17 May 2002
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 296 (5571) , 1250-1251
- https://doi.org/10.1126/science.1071808
Abstract
Many theories of aging have been proposed, but one of the most enduring is that expounding accumulated damage to the DNA as the root cause. In their Perspective, Hasty and Vijg comment on recent findings ( de Boer et al.) in a mouse model of a human disease that point to imperfect repair of DNA damage over a lifetime as an important contributor to the cellular deterioration associated with aging.Keywords
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