Nmr spectral analysis of kinetic data using natural lineshapes

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Abstract
An automated rapid data analysis scheme for NMR spectroscopy time course studies is presented. This method uses a high signal‐to‐noise reference spectrum collected at the beginning of a time course as a lineshape model to analyze subsequent low signal‐to‐noise data collected with higher time resolution. The method is fast (approximately 1 s to evaluate two peaks in a 2K spectrum) and easily implemented on NMR spectrometer computers. An application of this method to spectroscopic studies on the heart is provided.