Concurrent Upregulation of Urokinase Plasminogen Activator Receptor and CD11b during Tuberculosis and Experimental Endotoxemia
- 1 August 2001
- journal article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 69 (8) , 5182-5
- https://doi.org/10.1128/iai.69.8.5182-5185.2001
Abstract
Patients with tuberculosis had higher expression of monocyte urokinase receptor (uPAR) and CD11b than controls. In vitro, lipoarabinomannan and lipopolysaccharide (LPS) fromEscherichia colishared the ability to enhance uPAR and CD11b expression on monocytes and granulocytes. In healthy volunteers, LPS induced increases in monocyte and granulocyte uPAR and CD11b.Keywords
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