Chromosomal breakage in multiple endocrine adenomatosis (types I and II)

Abstract
Chromosomal analyses of cultured lymphocytes from 9 patients with familial multiple endocrine adenomatosis (MEA) syndrome type I from 6 families and 2 patients, father and daughter, with familial MEA syndrome type II showed an increased frequency of chromosomal breakage. The frequency of sister chromatid exchanges was not increased.