Conversion of the Laboratory Synthetic Route of the N-Aryl-2-benzothiazolamine R116010 to a Manufacturing Method

This publication has 12 references indexed in Scilit:

• Liarozole fumarate (R85246): a novel imidazole in the treatment of receptor positive postmenopausal metastatic breast cancer
  Breast Cancer Research and Treatment, 2000
• The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer
  Cancer, 1998
• Dynamic diastereomeric salt resolution of narwedine and its transformation to (−)-galanthamine
  Tetrahedron Letters, 1998
• The antiproliferative activity of all-trans-retinoic acid catabolites and isomers is differentially modulated by liarozole-fumarate in MCF-7 human breast cancer cells
  British Journal of Cancer, 1998
• Synthesis of LIAZALTM, a retinoic acid metabolism blocking agent (ramba) with potential clinical applications in oncology and dermatology
  Bioorganic & Medicinal Chemistry Letters, 1998
• Synthesis of N-benzyl-3-(S)-(+)-(4-fluorophenyl)-1,4-oxazin-2-one via a crystallisation induced asymmetric transformation
  Tetrahedron: Asymmetry, 1997
• Liarozole
  Drugs & Aging, 1996
• Stereo- and regioselective synthesis of chiral diamines and triamines from pseudoephedrine and ephedrine
  The Journal of Organic Chemistry, 1992
• Silafunctional compounds in organic synthesis. 33. Metalated allylaminosilane: a new, practical reagent for the stereoselective .alpha.-hydroxyallylation of aldehydes to erythro-1,2-diol skeletons
  The Journal of Organic Chemistry, 1987
• Acetyldiarylamines by arylation of acetanilides. Some applications and limitations
  The Journal of Organic Chemistry, 1978