A 14;19 TRANSLOCATION IN B‐CELL CHRONIC LYMPHOCYTIC LEUKEMIA: A NEW RECURRING CHROMOSOME ABERRATION

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Abstract
Four of 30 patients with a diagnosis of B‐CLL or prolymphocytic transformation of CLL, who had an adequate cytogenetic analysis, had abnormalities involving 14q32. Three of the 4 had a translocation involving chr. 19; in 2 of them it appeared to be t(14;19) (q32;q13‐1). The third patient probably had the same translocation. All 3 patients had received therapy prior to cytogenetic analysis.
Funding Information
  • National Computational Infrastructure (T 32-GM7190)
  • National Cancer Institute (CA 19266)
  • National Institutes of Health (T 32-GM7190)