SYNTHESIS OF 5-SUBSTITUTED 1-ANILINO-4-IMINOBARBITURIC ACIDS
- 1 November 1951
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 29 (11) , 1022-1027
- https://doi.org/10.1139/v51-119
Abstract
Substituted cyanoacetic esters have been reacted with 1-phenylsemicarbazide to give rise to 5-substituted-1-anilino-4-iminobarbituiric acids. The presence of an imino substituent in position 4 has been established by the hydrolysis of 5-benzyl-1-anilino-4-irninobarbituric acid into 5-benzyl-1-anilinobarbituric acid. The position of the anilino group has been ascertained by the transformation of 5-octyl-1-anilino-4-iminobarbituric acid into octylcyanoacetic phenylhydrazide, carbon dioxide, and ammonia.Keywords
This publication has 1 reference indexed in Scilit:
- Investigation of Pyrazole Compounds. I. The Reaction Product of Phenylhydrazine and Ethyl CyanoacetateJournal of the American Chemical Society, 1942