Dicumarol Fatality in Severe Hypertensive and Arteriosclerotic Cardiovascular Disease Despite Controlled Therapeutic Level
- 1 May 1950
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation
- Vol. 1 (5) , 1205-1208
- https://doi.org/10.1161/01.cir.1.5.1205
Abstract
The following case demonstrates fatal widespread hemorrhage resulting from the use of dicumarol at what is ordinarily considered a safe and desirable therapeutic level. It is suggested that the accompanying severe hypertensive and arteriosclerotic cardiovascular disease may have injured the contiguity of the vascular tree to such an extent that active diapedesis occurred in the presence of dicumarol.Keywords
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