Tolerability of -Blockade With Doxazosin as a Therapeutic Option for Symptomatic Benign Prostatic Hyperplasia in the Elderly Patient: A Pooled Analysis of Seven Double-Blind, Placebo-Controlled Studies
Open Access
- 1 May 1998
- journal article
- clinical trial
- Published by Oxford University Press (OUP) in The Journals of Gerontology: Series A
- Vol. 53 (3) , M201-M206
- https://doi.org/10.1093/gerona/53a.3.m201
Abstract
Background. Benign prostatic hyperplasia (BPH) is a common disorder in males, and its incidence increases with age. Safety results from trials with doxazosin therapy in elderly patients were collated and described. Methods. Safety data were collated from seven completed multicenter, double-blind, placebo-controlled studies of doxazosin in the treatment of BPH in older patients and analyzed according to age group (Results. Data for 341 patients aged ≥65 years (217 normotensive, 124 hypertensive) and 322 patients aged Conclusions. These studies show doxazosin to be equally well tolerated in young and old, normotensive and hypertensive patients with BPH.Keywords
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