Histochemical localization of acetylcholinesterase in the wall of cardiac blood vessels in the baboon, dog and vervet monkey
- 1 March 1982
- journal article
- research article
- Published by Springer Nature in Basic Research in Cardiology
- Vol. 77 (2) , 213-219
- https://doi.org/10.1007/bf01908174
Abstract
Histochemical methods were used to demonstrate acetylcholinesterase in the wall of cardiac blood vessels in the baboon, dog and vervet monkey. To remove cholinesterase-containing sympathetic nerves, some of the animals were treated with guanethidine for four weeks prior to being sacrificed. In cardiac muscle from the dog and the vervet monkey, cholinergic nerves were histochemically visualized in both small and large vessels. On the other hand, in cardiac muscle from baboons, cholinergic nerves were not seen in branches of the coronary artery with diameters between 0.6 mm to 1 mm and very few fibres were seen around smaller vessels of diameter less than 0.3 mm. The few fibres seen did not appear to penetrate the media of the vessels. These results support physiological findings that the baboon coronary vasculature is not innervated by parasympathetic cholinergic nerves. Bei Hunden und Affen wurden Acetylcholinesterase in der Wand der Blutgefäße des Herzens histochemisch demonstriert. Um Cholinesterase-haltige Sympathikusnerven zu beseitigen, wurden einige Tiere vor der Untersuchung 4 Wochen lang mit Gunanethidin behandelt. Im Herzmuskel vom Hund und Vervet-Affen wurden cholinerge Nervenfasern histochemisch sowohl in kleinen als auch in großen Gefäßen dargestellt. Andererseits wurden beim Herzmuskel von Pavianen in Koronararterienästen mit einem Durchmesser zwischen 0.6 und 1 mm keine cholinergen Nerven, um kleine Gefäße mit einem Durchmesser unter 0,3 mm nur sehr wenige Fasern festgestellt. Die erkennbaren Fasern schienen nicht die Media der Gefäße zu durchdringen. Diese Ergebnisse unterstützen physiologische Befunde, die darauf hinweisen, daß das Koronargefäßsystem des Pavians nicht parasympathisch innerviert ist.This publication has 15 references indexed in Scilit:
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