Mitochondria and Apoptosis
- 24 May 2001
- journal article
- review article
- Published by S. Karger AG in Neurosignals
- Vol. 10 (3-4) , 147-161
- https://doi.org/10.1159/000046884
Abstract
Apoptosis is a coordinated sequence of events culminating in the death of the cell. Many of these biochemical processes are regulated by the mitochondria, including the release of proapoptotic molecules in addition to the caspase-activating cofactor, cytochrome c. Pro- and antiapoptotic members of the Bcl-2 family regulate mitochondrial participation in cell death. Current models explaining cytochrome c release are discussed in light of mitochondrial structure and physiology.Keywords
This publication has 0 references indexed in Scilit: