Insect-Repellent Properties of 2-Ethylhexanediol-1,3

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Abstract
Extensive repellent trials made under laboratory and field conditions have shown 2-ethylhexanediol (known as Insect Repellent No. 612) to possess highly effective repellent properties against a variety of arthropod pests. In the laboratory it was repellent to Aades aegypti for an average of about 9 hours, to Anopheles quadrimaculatus for 1 hr. In the field it was repellent for an average of about 6 hrs. to salt marsh mosquitoes (Aedes cantator and A. sollicitans), for 3-4 hrs. to Anopheles punctulatus farauti, for 6 hrs. to black flies (Simulium spp.), for 4 hrs. to sand flies (Phlebotomus spp.), for 2 hrs. to stable flies (Stomoxys calcitrans) and fleas (Ctenocephalides felis and C. canis). Against chiggers (Euirombicula spp.) it was effective for several days if applied to clothing. Ethylhexanediol is a slightly viscous, colorless liquid having a mild odor somewhat like witchhazel. It is stable in storage or use. Extensive toxicological studies and large scale use by the military forces have indicated its safety and lack of irritant properties.

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