Transfer Factor and Leprosy

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Abstract
There is an increasing interest in the granulomatous diseases associated with suppression or abolition of delayed hypersensitivity responses in the face of unimpaired immunoglobin synthesis. Boeck's sarcoid and Hodgkin's disease are particularly well studied examples of this type of acquired dichotomy of immune responsiveness. In these diseases delayed hypersensitivity to most commonly encountered antigens of bacterial, fungal and viral origin is lost, as is the capacity to be actively sensitized by simple chemicals or BCG vaccination.Some insight into the mechanism of this selective involvement of delayed hypersensitivity has been achieved through studies on transfer factor, the subject of a . . .

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