Inhibition of rabbit tissue kininase by anti-(endo-oligopeptidase A) antibodies
- 1 July 1981
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 197 (1) , 85-93
- https://doi.org/10.1042/bj1970085
Abstract
Highly purified rabbit brain endo-oligopeptidase A injected into goats produced, after 60 days of immunization, antisera that specifically inhibit purified rabbit brain endooligopeptidase A. An immunoreactive kiniase having the same specificity as rabbit brain endo-oligopeptidase A for bradykinin was detected in several rabbit tissues. The highest amount of this immunoreactive kininase was found in the 25,000 g supernatant fraction (S fraction) of heart, liver, skeletal muscle, ovary, brain and testis homogenates, corresponding to 89, 86, 78, 59, 56 and 53%, respectively, of the whole kininase activity found in the S fraction.This publication has 20 references indexed in Scilit:
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