An LEA group 3 family member is involved in survival of C. elegans during exposure to stress
- 6 October 2004
- journal article
- Published by Wiley in FEBS Letters
- Vol. 577 (1-2) , 21-26
- https://doi.org/10.1016/j.febslet.2004.09.049
Abstract
In order to establish a functional role for late embryogenesis abundant (LEA) proteins in response to stress conditions in Caenorhabditis elegans, we silenced the expression of an LEA (Ce-lea-1) gene and determined the survival of worms under stress conditions. Ce-lea-1 transcription was induced during dehydration of C. elegans dauer juveniles. Following partial silencing of Ce-lea-1 transcription, we demonstrated a specific and significant reduction in worm survival during induction of desiccation, osmotic and heat stress. Together, these results establish a functional role for Ce-lea-1 in stress survival of C. elegans and suggest that Ce-lea-1 may function as a component that is common to the responses to the examined stress conditions.Keywords
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