Murine Recombinant lnterleukin-12 Increases the Acquisition of Allergic Contact Dermatitis in the Mouse
- 1 January 1995
- journal article
- research article
- Published by S. Karger AG in International Archives of Allergy and Immunology
- Vol. 106 (2) , 166-168
- https://doi.org/10.1159/000236839
Abstract
Interleukin-12 (IL-12) is a heterodimeric cytokine tha thas pleiotropic effects on the immune response. We have studied the effect of recombinant IL-12 on allergic contact dermatitis in the mouse. IL-12 substantially up-regulates the induction of sensitivity to the contact allergens dinitrofluorobenzene and oxazolone.Keywords
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