Destruction of the sympathetic ganglia in mammals by an antiserum to a nerve-growth protein
- 1 March 1960
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 46 (3) , 384-391
- https://doi.org/10.1073/pnas.46.3.384
Abstract
Antiserum against the salivary gland protein not only inactivates the protein, but, if injected alone into a newborn mammal, destroys its sympathetic cells without affecting other tissues or organs Daily injections for a period of 8 days results in the disappearance of up to 99% of the sympathetic nerve cells. The suggestion is made that the salivary glands are not the site of production of the nerve-growth agent but merely store it; the agent may possibly be manufactured in the mesenchyme.This publication has 6 references indexed in Scilit:
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